One hundred and eight years after the world’s first road traffic mortality (death) was recorded in 1896, more than 1.2 million people are still killed on roads worldwide every year and up to 50 million more still suffer various forms of morbidity (injuries and disabilities). Over the years, several road safety programmes have emphasised issues like acquisition and possession of driver's license, road permits, and vehicle insurance; including the need to check the state of the tyres, safety belts, spare wheels, lights, brakes, etc. Unfortunately, travelers, road safety officials and policy makers routinely ignore several health-related road safety issues, which occur before and during travels, and which might upset the human equilibrium and endanger safety to an even greater extent. Anyone travelling to spend more than five days in another environment, including traveling to the villages and other malaria-endemic areas during holidays and other festive seasons, must be aware that the duration of such visits and the traveller’s behaviour and lifestyle, determine the likelihood of exposure to many infectious agents. The traveller’s vision and eye health checks are extremely important. It is also a desirable road safety measure, to be armed with enough of necessary/regular personal, toilet and sanitary items that would last the duration of the trip, unless one is sure of their availability at the travel destination is assured. Wherever possible, road users/travelers should be armed with their health/medical information.. Suffice it to advise that travelers must be careful of what and where they eat before and during every trip. It must be emphasized that the loss and sufferings associated with road traffic deaths and injuries are almost always preventable.